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KLOW

Also known as KLOW blend, KPV + GHK-Cu + BPC-157 + TB-500 blend

Not approved in the USBlendHealing & recoverySkin & anti-agingAnti-inflammatory & immune

Last reviewed · Awaiting clinical review

Main safety concerns

KLOW is GLOW plus KPV. It exposes you to four peptides at once, including the copper part, so avoid it with a copper condition like Wilson's disease.

Educational information, not medical advice. If you have symptoms that worry you, contact a clinician or emergency services.

What is known

A four peptide blend that adds KPV to the GLOW mix of BPC-157, TB-500, and GHK-Cu.

Status:
A blend of peptides that are not FDA approved drugs. No blend like this is approved. Banned in sport.[1] [2] [3] [4] [5]
Strongest evidence for any claim:

See the evidence claim by claim

On this page

What it is and how it works

KLOW builds on the GLOW blend by adding KPV, a small peptide studied for calming inflammation. So one injection pairs tissue repair (BPC-157 and TB-500), skin and collagen support (GHK-Cu), and inflammation control (KPV). Like GLOW, the blend itself has not been tested in trials, and it looks blue when mixed because it contains GHK-Cu.

Evidence by claim

Each claim is graded on its own. Tap a grade to see what it does and does not mean.

  • The four peptide blend has been tested in a human trial.

    There is no trial of the KLOW mix. Evidence exists only for the separate peptides.

    No source cited for this claim.

  • Its parts support repair, skin, and lower inflammation.

    The individual peptides are studied mostly in animals, with limited human data.

    No source cited for this claim.

Reported side effects

  • WarningThe combined risks of all four peptides at onceYou take on the side effects of BPC-157, TB-500, GHK-Cu, and KPV together, in a ratio you cannot change.
  • CautionInjection site reactions(common)
  • CautionNausea, headache, or skin flushing(uncommon)

Interactions and combination risks

  • SeriousCopper lowering drugs (penicillamine, trientine, zinc)

    The GHK-Cu part adds copper, which works against these treatments.

  • SeriousActive cancer or a known tumor

    BPC-157 and TB-500 promote new blood vessel growth, which could in theory feed a tumor.

Who should avoid it

  • SeriousWilson's disease or other copper overload conditions

    The GHK-Cu part adds copper the body cannot clear safely.

  • SeriousActive or recent cancer

    The repair peptides encourage new blood vessel growth.

  • SeriousPregnancy or breastfeeding

    No safety data for any of the parts.

Dosing

Placed after the evidence and risks on purpose. Nothing here is a recommendation for you.

Community reported use, not tested in trials
Route(s)subcutaneous
Typical rangeDepends on the mg of each peptide in your vial. A common KLOW vial holds GHK-Cu 50 mg, BPC-157 10 mg, TB-500 10 mg, and KPV 10 mg.
FrequencyOften once daily
Cycle guidanceCommonly run for a few weeks.
NotesBecause it is a blend, one injection gives all four peptides in a fixed ratio that you cannot adjust. Check the label for the mg of each, then use the calculator.

For the equipment itself, see syringes, needles, and the rest of the kit.

Reconstitution

DiluentBacteriostatic water for multi dose vials, or sterile water for single use
ConcentrationReconstitute based on the total mg printed on the label. Because GHK-Cu is included, the mixed solution will look blue.
NotesSold as a lyophilized blend. A typical KLOW vial lists GHK-Cu, BPC-157, TB-500, and KPV separately, often around 80 mg total.

General reconstitution technique

Storage and stability

Dry powder (lyophilized)

TemperatureFreeze for long term storage, or 2 to 8 short term
Shelf lifeMany months when frozen
NotesKeep dry and out of light until you mix it.

After mixing

Temperature2 to 8 (refrigerated)
Shelf lifeAbout 4 weeks
NotesDo not freeze after mixing. A blue color is normal. Discard if it turns brown or cloudy.

General storage and stability guide

COA and purity notes

Common adulterantsunclear or missing mg for each peptide, missing the copper, so the solution is clear instead of blue, underdosed material
MislabelingA good blend lists the mg of all four peptides and comes with a COA. Because it contains GHK-Cu, the mixed solution should be blue.
NotesUnregulated research material sold as a fixed blend.

How to read a COA

Sources

  1. [1]Certain Bulk Drug Substances for Use in Compounding that May Present Significant Safety Risks

    U.S. Food & Drug Administration 2026 (opens source in a new tab)· Regulatory record

  2. [2]FDA Briefing Document, Pharmacy Compounding Advisory Committee, July 23 to 24, 2026: BPC-157 Related Bulk Drug Substances

    U.S. Food & Drug Administration 2026 (opens source in a new tab)· Regulatory record

  3. [3]FDA Briefing Document, Pharmacy Compounding Advisory Committee, July 23 to 24, 2026: TB-500 Related Bulk Drug Substances

    U.S. Food & Drug Administration 2026 (opens source in a new tab)· Regulatory record

  4. [4]FDA Briefing Document, Pharmacy Compounding Advisory Committee, July 23 to 24, 2026: KPV Related Bulk Drug Substances

    U.S. Food & Drug Administration 2026 (opens source in a new tab)· Regulatory record

  5. [5]World Anti-Doping Code International Standard: Prohibited List 2026

    World Anti-Doping Agency (WADA) 2026 (opens source in a new tab)· Regulatory record

Last reviewed 7 July 2026 · editorial status: reviewed