Educational information only. Not medical advice. SafePeptideUse sells nothing and is not a substitute for a qualified clinician. Talk to a healthcare professional before making any health decision.
← Peptide database

Wolverine

BlendHealing & recovery

Also known as: Wolverine stack, Wolverine blend, BPC-157 + TB-500 blend

A two peptide recovery blend of BPC-157 and TB-500, commonly called the Wolverine stack.

Safety:A blend gives you both peptides at once in a fixed ratio. It carries the risks of BPC-157 and TB-500 together, including the cancer caution that comes with promoting blood vessel growth.

2.What it is / mechanism

Wolverine combines BPC-157 and TB-500, two peptides studied for tissue repair. The idea is that they help healing through different but complementary paths: BPC-157 supports new blood vessel growth and gut and tendon repair, while TB-500 helps cells migrate to injured areas. The blend itself has not been tested in a trial, so what we know comes from the separate peptides. Both clear the blood within hours, so neither builds up.

3.What the evidence supports

  • No / insufficient dataThe blend as a whole has been tested in a human trial.

    There is no trial of the Wolverine mix. Evidence exists only for the separate peptides.

  • Animal data onlyIts parts support tissue repair and recovery.

    BPC-157 and TB-500 are studied mostly in animals, with limited human data. See their individual entries below.

4.Dosing

Anecdotal only
Route(s)subcutaneous
Typical rangeDepends on the mg of each peptide in your vial. Common vials hold roughly 10 mg of each, drawn as one daily dose. As singles that maps to about 250 to 500 mcg BPC-157 daily and a few mg of TB-500 per week.
FrequencyOften once daily
Cycle guidanceUsually 6 to 12 weeks, often a loading phase then maintenance.
NotesBecause it is a blend, one injection gives both peptides in a fixed ratio you cannot change. If you want to run TB-500 twice weekly and BPC-157 daily, as their single protocols suggest, you would need separate vials. See the component plot below to compare how each clears.

Component saturation

One injection of Wolverine delivers every peptide at once, but each clears at its own rate. This shows how quickly each component reaches its steady-state plateau.

Component saturation

0×0.3×0.6×0.9×1.2×day 02468101214
BPC-157half life 4 h · clears in ~20 h
TB-500half life 2.5 h · clears in ~12.5 h

Levels are shown as multiples of a single dose. Right after an injection you have about one dose in your blood; a short half life clears most of it within hours, so it does not stack up between injections. Widen the window to confirm it stays flat. Half lives are rough teaching estimates, not exact values.

5.Reconstitution

Vial sizes10 mg, 20 mg
DiluentBacteriostatic water for multi dose vials, or sterile water for single use
ConcentrationExample: a 20 mg blend vial (about 10 mg of each) plus 2 mL of water gives 10 mg/mL total, so 1 mg of the blend is 0.1 mL, which is 10 units on a U-100 syringe. Check your label, since ratios vary.
NotesSold as a pre mixed lyophilized blend, commonly around 10 to 20 mg total. The label should list the mg of BPC-157 and TB-500 separately.

Reconstitution calculator

Pick your vial size and how much water you add to see the draw volume and syringe units for a dose. Open the full calculator →

Inputs

Reminder: 1 mg = 1,000 mcg

mg

Total amount stated on the vial, e.g. 5 mg.

mL

How much diluent you draw into the vial.

mcg

Target dose per injection, in mcg. 1 mg = 1,000 mcg.

Result

Draw to

5 units

= 0.05 mL on your syringe

Concentration
5,000 mcg/mL
Per unit
50 mcg / unit
Doses per vial
40

Educational estimate only. Not medical or dosing advice. Verify every calculation independently before use.

General reconstitution technique →

6.Storage & stability

Lyophilized (dry)

TempFreeze for long term storage, or 2 to 8 short term
Shelf lifeMany months when frozen
NotesKeep dry and out of light until you mix it.

Reconstituted

Temp2 to 8 (refrigerated)
Shelf lifeAbout 2 to 4 weeks
NotesDo not freeze after mixing. Discard if cloudy or discolored.

General storage & stability guide →

7.Reported side effects

  • WarningThe combined risks of both peptides at onceYou take on the side effects of BPC-157 and TB-500 together, in a ratio you cannot change.
  • CautionInjection site reactions(common)
  • CautionTiredness or head fog, mostly early in a cycle(common)Often reported in the first week, largely from the TB-500 part, then it fades.

8.Interactions & stacking risks

  • SeriousActive cancer or a known tumor

    Both peptides promote new blood vessel growth, which could in theory support a tumor.

9.Contraindications / who should avoid

  • SeriousActive or recent cancer, or a strong family history

    Both parts encourage new blood vessel growth, a theoretical concern for feeding a tumor.

  • SeriousPregnancy or breastfeeding

    No safety data for either part.

10.COA & purity notes

Common adulterantsunclear or missing mg for each peptide, underdosed material, one peptide missing or swapped
MislabelingA good blend lists the mg of BPC-157 and TB-500 and comes with a COA.
NotesUnregulated research material sold as a fixed blend.

How to read a COA →

11.Sources

    Last reviewed 2026-07-07 · status: reviewed