Wolverine
Also known as Wolverine stack, Wolverine blend, BPC-157 + TB-500 blend
Last reviewed · Awaiting clinical review
Main safety concerns
A blend gives you both peptides at once in a fixed ratio. It carries the risks of BPC-157 and TB-500 together, including the cancer caution that comes with promoting blood vessel growth.
- SeriousAvoid if: Active or recent cancer, or a strong family history
- SeriousAvoid if: Pregnancy or breastfeeding
- WarningThe combined risks of both peptides at once
Educational information, not medical advice. If you have symptoms that worry you, contact a clinician or emergency services.
What is known
A two peptide recovery blend of BPC-157 and TB-500, commonly called the Wolverine stack.
On this page
What it is and how it works
Wolverine combines BPC-157 and TB-500, two peptides studied for tissue repair. The idea is that they help healing through different but complementary paths: BPC-157 supports new blood vessel growth and gut and tendon repair, while TB-500 helps cells migrate to injured areas. The blend itself has not been tested in a trial, so what we know comes from the separate peptides. Both clear the blood within hours, so neither builds up.
Evidence by claim
Each claim is graded on its own. Tap a grade to see what it does and does not mean.
The blend as a whole has been tested in a human trial.
There is no trial of the Wolverine mix. Evidence exists only for the separate peptides.
No source cited for this claim.Its parts support tissue repair and recovery.
BPC-157 and TB-500 are studied mostly in animals, with limited human data. See their individual entries below.
No source cited for this claim.
Reported side effects
- WarningThe combined risks of both peptides at onceYou take on the side effects of BPC-157 and TB-500 together, in a ratio you cannot change.
- CautionInjection site reactions(common)
- CautionTiredness or head fog, mostly early in a cycle(common)Often reported in the first week, largely from the TB-500 part, then it fades.
Interactions and combination risks
- SeriousActive cancer or a known tumor
Both peptides promote new blood vessel growth, which could in theory support a tumor.
Who should avoid it
- SeriousActive or recent cancer, or a strong family history
Both parts encourage new blood vessel growth, a theoretical concern for feeding a tumor.
- SeriousPregnancy or breastfeeding
No safety data for either part.
Dosing
Placed after the evidence and risks on purpose. Nothing here is a recommendation for you.
| Route(s) | subcutaneous |
|---|---|
| Typical range | Depends on the mg of each peptide in your vial. Common vials hold roughly 10 mg of each, drawn as one daily dose. As singles that maps to about 250 to 500 mcg BPC-157 daily and a few mg of TB-500 per week. |
| Frequency | Often once daily |
| Cycle guidance | Usually 6 to 12 weeks, often a loading phase then maintenance. |
| Notes | Because it is a blend, one injection gives both peptides in a fixed ratio you cannot change. If you want to run TB-500 twice weekly and BPC-157 daily, as their single protocols suggest, you would need separate vials. |
For the equipment itself, see syringes, needles, and the rest of the kit.
Reconstitution
| Vial sizes | 10 mg, 20 mg |
|---|---|
| Diluent | Bacteriostatic water for multi dose vials, or sterile water for single use |
| Concentration | Example: a 20 mg blend vial (about 10 mg of each) plus 2 mL of water gives 10 mg/mL total, so 1 mg of the blend is 0.1 mL, which is 10 units on a U-100 syringe. Check your label, since ratios vary. |
| Notes | Sold as a pre mixed lyophilized blend, commonly around 10 to 20 mg total. The label should list the mg of BPC-157 and TB-500 separately. |
General reconstitution technique
Units and volume arithmetic
Converts between an amount and syringe units for the vial and diluent you enter. It starts empty and does not suggest an amount. Open the full calculator
Result
Fill in steps 1 to 3 to see the arithmetic. Nothing here is a suggested amount.
Settings live in the address bar, so a pasted link reopens this calculator as you left it.
Educational arithmetic only. It does not choose an amount for you and is not medical or dosing advice. Verify every calculation independently.
Storage and stability
Dry powder (lyophilized)
| Temperature | Freeze for long term storage, or 2 to 8 short term |
|---|---|
| Shelf life | Many months when frozen |
| Notes | Keep dry and out of light until you mix it. |
After mixing
| Temperature | 2 to 8 (refrigerated) |
|---|---|
| Shelf life | About 2 to 4 weeks |
| Notes | Do not freeze after mixing. Discard if cloudy or discolored. |
COA and purity notes
| Common adulterants | unclear or missing mg for each peptide, underdosed material, one peptide missing or swapped |
|---|---|
| Mislabeling | A good blend lists the mg of BPC-157 and TB-500 and comes with a COA. |
| Notes | Unregulated research material sold as a fixed blend. |
Sources
[1]Certain Bulk Drug Substances for Use in Compounding that May Present Significant Safety Risks
U.S. Food & Drug Administration 2026 (opens source in a new tab)· Regulatory record[2]FDA Briefing Document, Pharmacy Compounding Advisory Committee, July 23 to 24, 2026: BPC-157 Related Bulk Drug Substances
U.S. Food & Drug Administration 2026 (opens source in a new tab)· Regulatory record[3]FDA Briefing Document, Pharmacy Compounding Advisory Committee, July 23 to 24, 2026: TB-500 Related Bulk Drug Substances
U.S. Food & Drug Administration 2026 (opens source in a new tab)· Regulatory record[4]World Anti-Doping Code International Standard: Prohibited List 2026
World Anti-Doping Agency (WADA) 2026 (opens source in a new tab)· Regulatory record
Last reviewed 7 July 2026 · editorial status: reviewed